Information about Vitamin B 12(Cyanocobalamine)

We Have to Know about Vitamin B 12(Cyanocobalamine) 

• Vitamin B12 is a complex organo-metallic compound with a cobalt atom. The preparation which is therapeutically used is Cyanocobalamine

Source

• Good sources are
• Liver, Kidney, Meat, Fish, Eggs, Milk and Cheese.
• Vitamin B]2 is not found in foods of vegetable origin.
• It is synthesized by bacteria in the colon
• In big Intestines (Colon) many nonharmful bacteria will normally live and they are useful to a human for providing useful nutrients.
• These microorganisms are called symbiotic organisms, unnecessary we should not take antibiotics for long periods

Function

• Vitamin B12 cooperates with Folic acid in the synthesis of DNA (It is required for cell division and cell normal function),
• Vitamin B12 has a separate biochemical role, unrelated to Folate, in the synthesis of fatty acids in myelin (nerve cell layer acts as an insulator)

Deficiency

• Results in
• Megaloblastic anaemia (pernicious anemia)
• Demyelization of neurological lesions in the spinal cord

Note :

• For its absorption, a factor from the stomach is required. Then it is absorbed only at a special site in the terminal ileum.
• Hence people suffering from any chronic disease of ileum will suffer from Vitamin – B12 deficiency.